Recombinant Human IFNGR1 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033429-10, PKSH033429-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: IFNGR1
Target Symptom: CD119; IFNGR; IMD27A; IMD27B; Interferon gamma receptor 1; IFNGR1
Research Area: Microbiology; immunology; Stem cells
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
UNIProt ID: P15260
Accession: P15260
Background: Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Sequence: Glu18-Ser245
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 28.7 kDa
Observed MW: 40-50 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only