Recombinant Human IGFBP3 protein(His tag)
Sizes: 20μg, 100μg
Catalogue Numbers: PDMH100044-20, PDMH100044-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: IGFBP3
Target Synonym: IBP-3; IGF-binding protein 3; IGFBP-3
UNIProt ID: P17936
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: P17936
Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity.Promotes testicular germ cell apoptosis.
Sequence: Met1-Lys291
Purity: > 80 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 32.5 kDa
Observed MW: 38-42 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only