Recombinant Human IL-1α Protein
Sizes: 20μg, 100μg
Catalogue Numbers: PDMH100025-20, PDMH100025-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: IL-1α
Target Synonym: IL-1 alpha; Hematopoietin-1; IL1A; IL1F1; Interleukin-1 alpha; IL1a
UNIProt ID: P01583
Research Areas: Cancer; Cardiovascular; Immunology;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: P01583
Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Sequence: Met1-Ala271
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 30.6 kDa
Observed MW: 35 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only