Recombinant Human IL7RA/CD127 Protein (Fc & His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033609-10, PKSH033609-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: IL7RA; CD127
Target Symptom: CD127; CDW127; IL-7R; IL-7R-alpha; IL7RA; ILRA; Interleukin-7 receptor subunit alpha; IL7R
Research Area: immunology; Stem cells
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Fc-His
UNIProt ID: P16871
Accession: P16871
Background: Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.
Sequence: Glu21-Gly236
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 52.8 kDa
Observed MW: 75 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only