Recombinant Human INPP5A Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033170-10, PKSH033170-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: INPP5A
Target Synonym: Type I inositol 1,4,5-trisphosphate 5-phosphatase; INPP5A
UNIProt ID: Q14642
Research Areas: Signal Transduction;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q14642
Background: Type I inositol 1, 4, 5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1, 4, 5-trisphosphate 5-phosphatase type I family. Type I inositol-1, 4, 5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
Sequence: Met 1-Val410
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 48.5 kDa
Observed MW: 45 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only