Recombinant Human KPNA2 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032670-10, PKSH032670-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: KPNA2
Target Synonym: Importin Subunit Alpha-2; Karyopherin Subunit Alpha-2; RAG Cohort Protein 1; SRP1-Alpha; KPNA2; RCH1; SRP1
UNIProt ID: P52292
Research Areas: Signal Transduction; immunology;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: P52292
Background: Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.
Sequence: Met 1-Phe529
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 20% Glycerol, pH 8.0 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 60.0 kDa
Observed MW: 60 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only