Recombinant Human LL-37 protein (GST tag)
Size: 100μg
Catalogue Numbers: PDEH100129-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: LL-37
Target Synonym: Cathelicidin antimicrobial peptide; CAMP_HUMAN; CAMP; 18 kDa cationic antimicrobial protein; CAP-18; hCAP-18; FALL39; HSD26
UNIProt ID: P49913
Research Areas: Microbiology
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-GST
Accession: P49913
Background: Antimicrobial protein that is an integral component of the innate immune system. Binds to bacterial lipopolysaccharides (LPS). Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2. Postsecretory processing generates multiple cathelicidin antimicrobial peptides with various lengths which act as a topical antimicrobial defense in sweat on skin. The unprocessed precursor form, cathelicidin antimicrobial peptide, inhibits the growth of Gram-negative E.coli and E.aerogenes with efficiencies comparable to that of the mature peptide LL-37 (in vitro).
Sequence: Leu 134-Ser 170
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 28.96 kDa
Observed MW: 32 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only