Recombinant Human LSAMP Protein (Fc Tag)(Active)
Size: 100μg
Catalogue Number: PKSH030896-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: LSAMP
Target Symptom: FLJ34254; FLJ35396; FLJ37216; FLJ54658; IGLON3; LAMP
Research Area: Neuroscience
Target Species: Human
Expression Host: HEK293 Cells
Application: ELISA
Fusion Tag: C-hFc
UNIProt ID: Q13449
Accession: Q13449
Background: The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system structures. The 64-68-kDa glycoprotein limbic system-associated membrane protein (LsAMP) is expressed on the surface of somata and proximal dendrites of neurons. These areas perform cognitive and autonomic functions; also learning and memory. The functional analysis indicates that LsAMP acts as a selective adhesion molecule; serving as a guidance cue for specific patterns of connectivity; which underlies the normal development of the limbic system. In animal studies there have been found that rats with increased level of anxiety had 1.6-fold higher expression of LsAMP gene in the periaqueductal gray compared to rats with low level of anxiety; indicating a possible role of LsAMP in the regulation of anxiety.
Activity: Immobilized recombinant human OPCML-His at 10 μg/mL can bind recombinant human LSAMP-Fc with a linear range of 31. 25-250 ng/ml.
Sequence: Met 1-Asn 315
Purity: > 97 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 59 kDa
Observed MW: 80-85 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only