Recombinant Human MAX Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033317-10, PKSH033317-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: MAX
Target Synonym: Protein Max; Class D Basic Helix-Loop-Helix Protein 4; bHLHd4; ; Myc-Associated Factor X; MAX; BHLHD4
Research Areas: Cancer; epigenetics and nuclear signal
Target Species: Human
Expression Host: E.coli
Fusion Tag: C-6His
Accession: NP_002373
Background: Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lung at high levels while lower levels are seen in the liver, kidney, and skeletal muscle. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. It may repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
Sequence: Met 1-Ser151
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM Imidazole, 250mM NaCl, pH 8.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 18.3 kDa
Observed MW: 21 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only