Recombinant Human MMP3 protein (His tag)
Sizes: 20μg, 100μg
Catalogue Numbers: PDMH100069-20, PDMH100069-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: MMP3
Target Synonym: Stromelysin-1; SL-1; Matrix metalloproteinase-3; Transin-1; MMP3; STMY1; CHDS6; MMP-3; SL-1; STMY; STR1
UNIProt ID: P08254
Research Areas: Signal Transduction; Cell biology; Cardiovascular; Cancer;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: P08254
Background: MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
Sequence: Met1-Cys477
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 52.36 kDa
Observed MW: 59 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only