Recombinant Human MOG Protein (E.coli, His Tag)
Size: 50μg
Catalogue Numbers: PKSH032768-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: MOG
Target Synonym: Myelin-Oligodendrocyte Glycoprotein; MOG; BTN6; BTNL11; MOGIG2; NRCLP7
UNIProt ID: Q16653
Research Areas: Neuroscience
Target Species: Human
Expression Host: E.coli
Fusion Tag: C-6His
Accession: Q16653
Background: Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals; namely experimental autoimmune encephalomyelitis (EAE); in rodents and monkeys.
Sequence: Gly30-Gly154
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 15.2 kDa
Observed MW: 18 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only