Recombinant Human Periostin/OSF-2 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032880-10, PKSH032880-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Periostin; OSF-2
Target Synonym: Osteoblast-specific factor 2; OSF-2; POSTN; Periostin; PDLPOSTN; periostin; PN
UNIProt ID: Q15063
Research Areas: Signal Transduction; Tags & Cell Markers; Cardiovascular; Cancer;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q15063-2
Background: Osteoblast-Specific Factor OSF-2 (POSTN, Periostin, OSF-2) is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. Periostin is a disulfide linked 90kDa bone adhesion protein secreted by osteoblasts and osteoblast-like cell lines and the protein is an attachment agent for osteoblasts. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumor suppressor. It is synthesized by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells.
Sequence: Asn22-Gln779
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCI, 150mM NaCl, pH8.0 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 85.6 kDa
Observed MW: 85-90 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only