Recombinant Human PGRL/IGSF8 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032581-10, PKSH032581-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: PGRL; IGSF8
Target Synonym: Immunoglobulin Superfamily Member 8; IgSF8; CD81 Partner 3; Glu-Trp-Ile EWI Motif-Containing Protein 2; EWI-2; Keratinocytes-Associated Transmembrane Protein 4; KCT-4; LIR-D1; Prostaglandin Regulatory-Like Protein; PGRL; CD316; IGSF8; CD81P3; EWI2; KCT4
UNIProt ID: Q969P0
Research Areas: Microbiology; Cancer; immunology
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q969P0
Background: Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.
Sequence: Arg28-Thr579
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 59.6 kDa
Observed MW: 75 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only