Recombinant Human PPIH Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032879-10, PKSH032879-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: PPIH
Target Synonym: Peptidyl-Prolyl Cis-Trans Isomerase H; PPIase H; Rotamase H; Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H; CypH; U-snRNP-Associated Cyclophilin SnuCyp-20; USA-CYP; PPIH; CYP20; CYPH
UNIProt ID: O43447
Research Areas: Signal Transduction; epigenetics and nuclear signal;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: O43447
Background: Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.
Sequence: Met 1-Met 177
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 21.4 kDa
Observed MW: 18 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only