Recombinant Human Semenogelin-1/SEMG1 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033025-10, PKSH033025-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Semenogelin-1; SEMG1
Target Synonym: Semenogelin-1; Semenogelin I; SGI; SEMG1; SEMG; Alpha-Inhibin-92; Alpha-Inhibin-31; Seminal Basic Protein
UNIProt ID: P04279
Research Areas: Cell biology
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P04279
Background: Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alpha-inhibin-92 and alpha-inhibin-31 are produced; they inhibit the secretion of pituitary follicle-stimulating hormone. At the same time, it breaks down the gel matrix, allowing the spermatozoa to move more freely.
Sequence: Gln24-Thr402
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Hac-NaAc, 150mM NaCl, pH 4.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 43.8 kDa
Observed MW: 29-54 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only