Recombinant Human SerpinA3/AACT Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033032-10, PKSH033032-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: SerpinA3; AACT
Target Synonym: Alpha-1-Antichymotrypsin; ACT; Cell Growth-Inhibiting Gene 24/25 Protein; Serpin A3; SERPINA3; AACT; GIG24; GIG25; MGC88254; SERPINA3
UNIProt ID: P01011
Research Areas: Cell biology; Cardiovascular; Neuroscience
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P01011
Background: Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease.
Sequence: His24-Ala423
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 46.3 kDa
Observed MW: 73 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only