Recombinant Human SQSTM1/ p62 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100245-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: SQSTM1; p62
Target Synonym: A170; DMRV; EBI 3 associated protein p60; EBIAP; FTDALS3; ORCA; OSF-6; OSIL; p60; P62b; PDB 3; PDB3; Sequestosome 1; SQSTM 1; STAP; STONE14; ZIP3
UNIProt ID: Q13501
Research Areas: Signal Transduction; Epigenetics and Nuclear Signaling; Cardiovascular; Cancer; Neuroscience
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: Q13501
Background: Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
Sequence: Ser 3-Lys 102
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 10.89 kDa
Observed MW: 15 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only