Recombinant Human ST6GAL1 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033362-10, PKSH033362-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: ST6GAL1
Target Symptom: Beta-Galactoside Alpha-2; 6-Sialyltransferase 1; Alpha 2; 6-ST 1; B-Cell Antigen CD75; CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2; 6-Sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1; ST6GAL1; SIAT1
Research Area: Signal Transduction; immunology;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
UNIProt ID: P15907
Accession: P15907
Background: The ST6GAL1 gene encodes β-Galactosamide α-2; 6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2; 6-sialylation of Galβ1; 4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
Sequence: Lys27-Cys406
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 44.6 kDa
Observed MW: 41-48 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only