Recombinant Human Tryptase β-2/TPSB2 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033154-10, PKSH033154-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Tryptase β-2; TPSB2
Target Synonym: Tryptase Beta-2; Tryptase-2; Tryptase II; TPSB2; TPS2
UNIProt ID: P20231
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P20231
Background: Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
Sequence: Ala19-Pro275
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 29.6 kDa
Observed MW: 30 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only