Recombinant Human XPNPEP3 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033229-10, PKSH033229-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: XPNPEP3
Target Symptom: Probable Xaa-Pro Aminopeptidase 3; X-Pro Aminopeptidase 3; Aminopeptidase P3; APP3; XPNPEP3
Research Area: Signal Transduction; metabolism;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
UNIProt ID: Q9NQH7
Accession: Q9NQH7
Background: Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.
Sequence: Met 1-Ser507
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 25mM Tris, 1mM DTT, pH 7.3.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 60.2 kDa
Observed MW: 65 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only