Recombinant LXR alpha Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81580-50, E-AB-81580-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: LXR alpha
Target Synonym: NR1H3; LXR-a; LXRA; RLD-1; LXR alpha
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB, IHC-P
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R07-6A4
UNIProt ID: Q13133
Background: NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human LXR alpha
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:20-1:100
Calculated MW: 50kDa
Observed MW: 50kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only