Recombinant Mouse PSGL-1/CD162 Protein (aa 42-307, Fc Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSM041283-10, PKSM041283-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: PSGL-1; CD162
Target Synonym: CD162; Psgl-1; Psgl1; Selp1; CLA; PSGL1; PSGL-1
UNIProt ID: Q62170
Target Species: Mouse
Expression Host: HEK293 Cells
Fusion Tag: C-Fc
Accession: Q62170
Background: P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Sequence: Gln42-Cys307
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 54.7 kDa
Observed MW: 90 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only