Recombinant Mouse TGM2/Transglutaminase 2 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSM041171-10, PKSM041171-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: TGM2; Transglutaminase 2
Target Synonym: Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue transglutaminase; Transglutaminase C; TGase-2
UNIProt ID: P21981
Target Species: Mouse
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P21981
Background: Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme, It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Sequence: Ala2-Ala686
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20%Glycerol, pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 78.0 kDa
Observed MW: 70-80 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only