Recombinant NEDD4 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81585-50, E-AB-81585-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: NEDD4
Target Synonym: NEDD4; NEDD4-1; RPF1
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R06-7C3
UNIProt ID: P46934
Background: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human NEDD4
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:2000-1:3000
Calculated MW: 149kDa
Observed MW: 115kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only