Recombinant PKR Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81597-50, E-AB-81597-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: PKR
Target Synonym: EIF2AK2; EIF2AK1; PKR; PPP1R83; PRKR; Eif2ak2
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R04-3F2
UNIProt ID: Q03963
Background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of mouse PKR
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000
Calculated MW: 62kDa
Observed MW: 74kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only