Recombinant Rhesus Macaque TNF Receptor II/TNF RII/TNFRSF1B/CD120b (C-Fc)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSQ050114-10, PKSQ050114-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: TNFRSF1B; CD120b
Target Synonym: TNF-RII; TNFRII; TNF RII; Tumor necrosis factor receptor superfamily member 1b; Tnfrsf1b
UNIProt ID: F7EAF8
Target Species: Rhesus Macaque
Expression Host: HEK293 Cells
Fusion Tag: C-Fc
Accession: F7EAF8
Background: Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains: Tumor necrosis factor receptor superfamily member 1b and membrane form and Tumor necrosis factor-binding protein 2. TNFRSF1B is a receptor with high affinity for TNFSF2/TNF-α and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-α. TNFRSF1B mediates most of the metabolic effects of TNF-α. TNF-α-induced apoptosis suggests that it regulates TNF-α function by antagonizing its biological activity.
Sequence: Leu23-Asp257
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 52 kDa
Observed MW: 60-80 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only