Recombinant STAT5b Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81513-50, E-AB-81513-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: STAT5b
Target Synonym: STAT5; STAT5B
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R08-2I8
UNIProt ID: P51692
Background: STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of human STAT5b
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:1000-1:2000 IHC 1:50-1:100
Calculated MW: 90kDa
Observed MW: 90kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only