Recombinant Transmembrane Protein 173 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81615-50, E-AB-81615-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Transmembrane Protein 173
Target Synonym: endoplasmic reticulum IFN stimulator; Endoplasmic reticulum interferon stimulator; ERIS; FLJ38577; hMITA; hSTING; Mediator of IRF3 activation; MITA; Mitochondrial mediator of IRF3 activation; MPYS; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; NET23; Stimulator of interferon genes; Stimulator of interferon genes protein; STING; TM173; Tmem173; Transmembrane protein 173
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB, IHC-P
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R06-9A7
UNIProt ID: Q86WV6
Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of human TMEM173
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:50-1:100
Calculated MW: 42kDa
Observed MW: 40kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only