REST Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-17813-60, E-AB-17813-120, E-AB-17813-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: REST
Target Synonym: Neural Restrictive Silencer Factor; Neural-restrictive silencer factor; Neuron Restrictive Silencer Factor; NRSF; RE1 silencing transcription factor; RE1-silencing transcription factor; Repressor binding to the X2 box; rest; REST protein; REST; X2 box repressor; XBR
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q13127
Background: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.
Concentration: 1 mg/mL
Immunogen: Synthetic peptide of human REST
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only