RIP3 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-60962-60, E-AB-60962-120, E-AB-60962-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RIP3
Target Synonym: RIPK3; RIP3
Research Areas: Cancer, Cell Biology, Immunology, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9Y572
Background: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human RIP3 (NP_006862.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only