RRAGA Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-67911-60, E-AB-67911-120, E-AB-67911-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RRAGA
Target Synonym: RRAGA; FIP-1; FIP1; RAGA
Research Areas: Cancer, Cell Biology, Metabolism, Microbiology, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q7L523
Background: Ras-related GTP-binding protein Ais aproteinthat in humans is encoded by theRRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human RRAGA (NP_006561.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:50-1:100
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only