SCCPDH Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-19034-60, E-AB-19034-120, E-AB-19034-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SCCPDH
Target Synonym: CGI 49; CGI49; FLJ43187; Probable saccharopine dehydrogenase; Saccharopine dehydrogenase; SCCPDH; SCPDH
Research Areas: Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q8NBX0
Background: SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C.elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3, 000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Concentration: 1.5 mg/mL
Immunogen: Fusion protein of human SCCPDH
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Calculated MW: 47 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only