SCNN1A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-67674-60, E-AB-67674-120, E-AB-67674-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SCNN1A
Target Synonym: SCNN1A; BESC2; ENaCa; ENaCalpha; SCNEA; SCNN1
Research Areas: Metabolism, Neuroscience, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P37088
Background: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human SCNN1A (NP_001029.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only