SECISBP2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-61334-60, E-AB-61334-120, E-AB-61334-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SECISBP2
Target Synonym: SECISBP2; SBP2
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q96T21
Background: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human SECISBP2 (NP_076982.3).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200 IF 1:50-1:100
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only