SERPINB4 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-52213-60, E-AB-52213-120, E-AB-52213-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SERPINB4
Target Synonym: Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor (leucine serpin); SCCA 2; SCCA-2; SCCA1; SCCA2; SCCA2/SCCA1 fusion protein; Serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 4; Serpin B4; Serpin peptidase inhibitor; clade B (ovalbumin); member 4; SERPINB 4; SERPINB4; SPB4; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Research Areas: Cancer, Cell Biology, Immunology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P48594
Background: The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. SERPINB4 (Serpin Family B Member 4) is a Protein Coding gene. Diseases associated with SERPINB4 include Squamous Cell Carcinoma and Chromosome 18Q Deletion Syndrome. Among its related pathways are Amoebiasis. GO annotations related to this gene include enzyme binding and protease binding. An important paralog of this gene is SERPINB3.
Concentration: 0.72 mg/mL
Immunogen: Fusion protein of human SERPINB4
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only