SETMAR Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-61336-60, E-AB-61336-120, E-AB-61336-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SETMAR
Target Synonym: SETMAR; METNASE; Mar1
Research Areas: Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q53H47
Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Concentration: 1 mg/mL
Immunogen: Recombinant fusion protein of human SETMAR
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW: 40kDa/62kDa/78kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only