SIGLEC5 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-11046-60, E-AB-11046-120, E-AB-11046-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SIGLEC5
Target Synonym: CD170; CD170 antigen; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OB-BP2; OBBP2; Obesity-binding protein 2; Sialic acid binding Ig-like lectin 5; Sialic acid binding immunoglobulin-like lectin 5; Sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; SIGL5; Siglec-5; Siglec-F variant; Siglec5; Siglecf
Research Areas: Cancer, Immunology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: O15389
Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Concentration: 0.2 mg/mL
Immunogen: Recombinant protein of human SIGLEC5
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:25-1:100
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only