SLC22A17 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-12870-60, E-AB-12870-120, E-AB-12870-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SLC22A17
Target Synonym: 24p3 receptor; 24p3R; BOCT; BOIT; Brain type organic cation transporter; Brain-type organic cation transporter; hBOIT; Lipocalin-2 receptor; Neutrophil gelatinase associated lipocalin receptor; Neutrophil gelatinase-associated lipocalin receptor; NGAL receptor; NgalR; NGALR2; NGALR3; OTTHUMP00000082690; OTTHUMP00000082691; Potent brain type organic ion transporter; S22AH; Slc22a17; Solute carrier family 22 member 17; Solute carrier family 22 organic cation transporter member 17
Research Areas: Cancer, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q8WUG5
Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
Concentration: 0.3 mg/mL
Immunogen: Synthetic peptide of human SLC22A17
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:25-1:100
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only