SLC25A19 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-65956-60, E-AB-65956-120, E-AB-65956-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SLC25A19
Target Synonym: SLC25A19; DNC; MCPHA; MUP1; THMD3; THMD4; TPC
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9HC21
Background: This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human SLC25A19 (NP_068380.3).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only