2019-nCoV NP Antibody (6G9)
Size: 1mg
Catalogue Number: EPT257-1
Citations, Manuals and MSDS Available upon request.
Description: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Background: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Biological Activity: Immobilized 2019-nCoV NP Antibody(6G9)-Fc(Cat#DA027) at 5μg/ml(100 μl/well) can bind 2019-nCoV Nucleocapsid Protein-His(Cat#DRA31). The ED50 of 2019-nCoV Nucleocapsid Protein-His(Cat#DRA31) is 0. 1-0. 7 ng/ml.
Storage: 24 months from manufacturing at <-20 °C; 1 month, 2 to 8 °C under sterile conditions
Delivery Conditions: The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Research Use Only.