Native Crotalus adamanteus venom Phosphodiesterase I
Size: 100 U
Catalogue Number: NATE-0512
Citations, Manuals and MSDS Available upon request.
Product Description: Venom exonuclease (Phosphodiesterase I) successively hydrolyzes 5'-mononucleotides from 3'-OH-terminated ribo- and deoxyribo-oligonucleotides. The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. Phosphodiesterase is inhibited by reducing agents such as glutathione, cysteine and ascorbic acids. It is completely inhibited by 5mM EDTA while ATP, ADP and AMP are partial inhibitors. The enzyme has an absolute requirement for Mg2+.
Storage: â20°C
Activity: > 20 units per mg dry weight
CAS#: 9025-82-5
Research Use Only