APC Anti-Mouse CD119 Antibody (GR-20)
Sizes: 50T, 100T
Catalogue Numbers: APC-30207-50, APC-30207-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD119
Form: Liquid
Conjugation: APC
Conjugation Information: APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: GR-20
Isotype: IgG2a, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
Synonyms: CD119|IFN-gamma-R-alpha|IFN-gamma-R1|Ifngr1|Interferon gamma receptor 1
Uniprot ID: P15261
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 15979
Category: Flow cytometryometry Antibodies
Research Use Only