APC Anti-Human/Mouse KLRG-1 Antibody [2F1] - E-AB-F1273UE

APC Anti-Human/Mouse KLRG-1 Antibody [2F1]

Size: 100μg

Catalogue Number: E-AB-F1273UE-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: KLRG-1

Target Synonym: MAFA, 2F1-Ag,

Conjugation: APC

Host: Syrian Hamster

Species Reactivity: Human, Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Syrian Hamster IgG

Clone No.: 2F1

UNIProt ID: Q96E93, O88713,

Background: Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG22 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09763E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 1, 021, 950, 928

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag