Biotin Anti-Human CD62L Antibody (DREG56)
Sizes: 25μg, 100μg
Catalogue Numbers: Biotin-30091U-25, Biotin-30091U-100
Citations, Manuals and MSDS Available upon request.
Target: Human CD62L
Form: Liquid
Conjugation: Biotin
Host: Mouse
Clonality: Monoclonal
Clone ID: DREG56
Isotype: IgG1, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Synonyms: CD62L| CD62 antigen-like family member L| L-selectin| LAM-1| LECAM1| Lnhr| Ly-22| Ly22| Lymph node homing receptor| Sell
Uniprot ID: P14151
Reactivity: Human
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 6402
Category: Flow cytometryometry Antibodies
Research Use Only