Biotin Anti-Mouse CD49b/pan-NK cells Antibody (DX5)
Sizes: 25μg, 100μg
Catalogue Numbers: Biotin-30097U-25, Biotin-30097U-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD49b/pan-NK cells
Form: Liquid
Conjugation: Biotin
Host: Rat
Clonality: Monoclonal
Clone ID: DX5
Isotype: IgM, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Synonyms: CD49 antigen-like family member B| CD49b| Collagen receptor| GPIa| Integrin alpha-2| Platelet membrane glycoprotein Ia| VLA-2 subunit alpha| pan-NK cells
Uniprot ID: Q62469
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 16398
Category: Flow cytometryometry Antibodies
Research Use Only