Biotin Anti-Mouse CD86 Antibody (GL-1)
Sizes: 25μg, 100μg
Catalogue Numbers: Biotin-30025U-25, Biotin-30025U-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD86
Form: Liquid
Conjugation: Biotin
Host: Rat
Clonality: Monoclonal
Clone ID: GL-1
Isotype: IgG2a, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Synonyms: Activation B7-2 antigen| Cd86| ETC-1| Early T-cell costimulatory molecule 1| T-lymphocyte activation antigen CD86
Uniprot ID: P42082
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 12524
Category: Flow cytometryometry Antibodies
Research Use Only