FineTest®488 Anti-Mouse CD117/c-Kit Antibody (2B8)
Sizes: 25μg, 100μg
Catalogue Numbers: F488-30136U-25, F488-30136U-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD117/c-Kit
Form: Liquid
Conjugation: FineTest®488
Conjugation Information: FineTest® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: 2B8
Isotype: IgG2b, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Synonyms: CD117| Kit| Mast/stem cell growth factor receptor Kit| Proto-oncogene c-Kit| SCFR| Tyrosine-protein kinase Kit| c-Kit
Uniprot ID: P05532
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 16590
Category: Flow cytometryometry Antibodies
Research Use Only