FineTest®647 Anti-Human CD328/Siglec-7 Antibody (FN25H)
Sizes: 20T, 100T
Catalogue Numbers: F647-30337-20, F647-30337-100
Citations, Manuals and MSDS Available upon request.
Target: Human CD328
Form: Liquid
Conjugation: FineTest®647
Conjugation Information: FineTest® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).
Host: Rabbit
Clonality: Monoclonal
Clone ID: FN25H
Isotype: IgG
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Synonyms: Sialic acid-binding Ig-like lectin 7|Siglec-7|Adhesion inhibitory receptor molecule 1 (AIRM-1)|CDw328|D-siglec|QA79 membrane protein|p75|SIGLEC7|AIRM1|CD328
Uniprot ID: Q9Y286
Reactivity: Human
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 27036
Research Area: Neuroscience, Immunology, Signal Transduction
Category: Flow cytometryometry Antibodies
Research Use Only