FineTest®700 Anti-Mouse CD172a/SIRPα Antibody (P84)
Sizes: 50T, 100T
Catalogue Numbers: F700-30268-50, F700-30268-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD172a/SIRPα
Form: Liquid
Conjugation: FineTest®700
Conjugation Information: FineTest® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: P84
Isotype: IgG1, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
Synonyms: BIT|CD172 antigen-like family member A|P84|PTPNS1|SHPS-1|SIRPα
Uniprot ID: P97797
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 19261
Category: Flow cytometryometry Antibodies
Research Use Only