FITC Anti-Mouse IL-10 Antibody (JES5-16E3)
Sizes: 25μg, 100μg
Catalogue Numbers: FITC-30146U-25, FITC-30146U-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse IL-10
Form: Liquid
Conjugation: FITC
Conjugation Information: FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: JES5-16E3
Isotype: IgG2b, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated Antibody production); and promotes mast cell proliferation in combination with IL-4.
Synonyms: CSIF| Cytokine synthesis inhibitory factor| IL-10| Interleukin-10
Uniprot ID: P18893
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 16153
Category: Flow cytometryometry Antibodies
Research Use Only